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New Molecular Sensor Tracks Energy Use at the Subcellular Level

WCM Newsroom
ATP sensor targeted to mitochondria in primary neurons. Green indicates the presence of ATP, while red independently labels the sensor.
8 months ago

Extracellular ATP/adenosine dynamics in the brain and its role in health and disease

Frontiers
Extracellular ATP and adenosine are neuromodulators that regulate numerous neuronal functions in the brain. Neuronal activity and brain insults such as...
6 months ago

Mitochondrial ATP synthesis is essential for efficient gametogenesis in Plasmodium falciparum

Nature
We show that the male gametocyte mitochondrion is less active than that of female gametocytes and more sensitive to antimalarials targeting mitochondrial...
2 months ago

The Origins Of ATP Dependence In Biological Nitrogen Fixation

Astrobiology News
We investigate the evolutionary necessity of ATP by experimentally reconstructing an ancestral variant of the key N2 reducing enzyme nitrogenase...
10 months ago

Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain

Frontiers
ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms.
6 months ago

Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F

Nature
Mitochondrial adenosine triphosphate (ATP) synthase uses the proton gradient across the inner mitochondrial membrane to synthesize ATP.
11 months ago

ATP as a biological hydrotrope

Science | AAAS
We show that adenosine triphosphate (ATP) has properties of a biological hydrotrope. It can both prevent the formation of and dissolve previously formed...
91 months ago

Life’s energy currency ATP made using electricity from the grid for the first time

Chemistry World
The gap between manmade electricity and the biochemical energy that powers life, adenosine triphosphate (ATP), has been directly bridged using a new to nature...
16 months ago

Scientists Electrify Biology by Converting Current Into the Chemical Fuel of Cells

SingularityHub
Researchers created an artificial metabolic pathway that can directly convert electricity into ATP using a cocktail of enzymes.
16 months ago

Seminal Study Sheds Light on Cell Mitochondria

SBU News
A promising study toward a better understanding of mitochondrial adenosine triphosphate (ATP) synthase.
11 months ago